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Paranoia - All cannabinoids are capable of inducing paranoia at substantial doses or with Long-term administration.As Beforehand reported, JWH-018 (6 mg/kg) [21] rapidly decreased HR, inducing deep bradycardia and bradyarrhythmia alternated by sudden episodes of tachyarrhythmia that persisted up to 6 hrs. In addition, PD values substantially lessen